奚菊群,女,博士,講師。2003年6月畢業(yè)于
揚(yáng)州大學(xué)化學(xué)化工學(xué)院,同年保送至本校攻讀化學(xué)化工學(xué)院物理化學(xué)專(zhuān)業(yè)博士學(xué)位
f1411.cn,開(kāi)展納米膠束和納米脂質(zhì)體等藥物載體方面的研究。2008年6月獲得博士學(xué)位,同年7月至揚(yáng)州大學(xué)醫(yī)學(xué)院藥學(xué)系工作,從事藥劑學(xué)的教學(xué)與科研工作。目前主要從事基于納米技術(shù)的新型藥物輸送系統(tǒng)設(shè)計(jì)、構(gòu)建與表征。主要研究?jī)?nèi)容包括采用高分子材料學(xué)、生物材料學(xué)及有機(jī)合成化學(xué)等的方法和原理
f1411.cn,通過(guò)分子設(shè)計(jì)、改性和修飾等技術(shù)合成可生物降解、安全的相關(guān)納米材料,包括多糖類(lèi)高分子、功能化兩親性高分子、脂質(zhì)材料和無(wú)機(jī)納米材料等,并對(duì)其性狀、結(jié)構(gòu)、生物物理特性、載藥與藥物釋放特性、特異性的納米效應(yīng)等進(jìn)行表征。
發(fā)表的研究論文:
(1) Juqun Xi, Rong Guo, Xia Guo, Interactions of hemoglobin with lecithin liposomes, Colloid Polym. Sci. 2006 (284) 1139-1145
(2) Juqun Xi, Rong Guo, Interactions between flavonoids and hemoglobin in lecithin liposomes, Int. Biol. Macromol. 2007 (40) 305-311.
(3) Juqun Xi, Rong Guo, Acid–base equilibrium of puerarin in CTAB micelles, J. Pharmaceut. Biomed. 2007 (43) 111-118.
(4) Juqun Xi, Rong Guo, Studies on molecular interactions between puerarin and PC liposomes, Chinese Sci. Bull. 2007 (52) 2612-2617.
(5) Juqun Xi, Rong Guo, Interactions of puerarin with micelles: pKa shifts and thermodynamics, J. of Solution Chem. 2008 (37) 107-118.
(6) Juqun Xi, Rong Guo, Effects of pH and micelle on the radical scavenging ability of puerarin, J. Disper. Sci. Technol. 2009 (30) 857-864.
(7) Juqun Xi, Rong Guo, Studies on the interactions between genistein and copolymer F127, J. Solution Chem. 2009 (38) 1588-1600.
(8) Yongsheng Wang, Rong Guo, Juqun Xi, Comparative studies of interactions of hemoglobin with single-chain and with gemini surfactants, J. Colloid Interf. Sci. 2009(331)470– 475.
(9)Juqun Xi, Lei Fan, Study on the binding of puerarin to bovine serum albumin by isothermal titration calorimetry and spectroscopic approaches, J. Therm. Anal. Calorim. 2010 (102)217–223.